Diseases and Conditions

Enlarged spleen (splenomegaly)

Overview

Your spleen is an organ that sits just below your left rib cage. Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen. An enlarged spleen is also known as splenomegaly (spleh-no-MEG-uh-lee).

An enlarged spleen usually doesn't cause symptoms. It's often discovered during a routine physical exam. A doctor usually can't feel the spleen in an adult unless it's enlarged. Imaging and blood tests can help identify the cause of an enlarged spleen.

Treatment for an enlarged spleen depends on what's causing it. Surgery to remove an enlarged spleen usually isn't needed, but sometimes it's recommended.

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