Overview

Leiomyosarcoma is a rare type of cancer that begins in smooth muscle tissue. Smooth muscle tissue is found in many areas of the body, such as the digestive system, urinary system, blood vessels and uterus.

Leiomyosarcoma most often begins in the abdomen or uterus. It starts as a growth of abnormal cells and often grows quickly to invade and destroy normal body tissue.

Signs and symptoms of leiomyosarcoma depend on where the cancer starts. They might include pain, weight loss, and a growing lump or swelling that can be felt through the skin.

Leiomyosarcoma is a type of soft tissue sarcoma, which is a broad category of cancers that begin in the tissues that connect, support and surround other body structures.