Overview

Sweet's syndrome, also called acute febrile neutrophilic dermatosis, is an uncommon skin condition. It causes fever and a painful skin rash that appears mostly on the arms, face and neck.

The cause of Sweet's syndrome isn't known, but it's sometimes triggered by an infection, illness or medication. It can also occur with some types of cancer.

The most common treatment for Sweet's syndrome is corticosteroid pills, such as prednisone. Signs and symptoms may go away after just a few days of treatment but can come back again.