Do women have to take post-menopausal hormone therapy after oophorectomy? Why might a woman opt for oophorectomy over mastectomy? Content What is oophorectomy? Who can consider prophylactic oophorectomy? How much can oophorectomy reduce the risk of cancer? What are the risks of oophorectomy? Do you need postmenopausal hormone therapy after oophorectomy? Are there alternatives to oophorectomy for preventing ovarian cancer? Doesn't mastectomy offer a greater reduction in breast cancer risk? Why might a person opt for oophorectomy over mastectomy? What questions should you ask your doctor?