Diseases and Conditions
Cavernous malformations
What you can do
Overview
Symptoms
Causes
Risk factors
Complications
Diagnosis
Treatment
Preparing for an appointment
Causes
Most CCMs occur as a single formation, without an apparent cause and without any family history.
However, roughly 20 percent of affected people have a familial (inherited) form of the disorder. In many cases, such people can identify similarly affected family members, most often with multiple malformations. A diagnosis of the inherited form can be confirmed by genetic testing.
Some CCMs can also occur following focal brain radiation therapy.