Complications

The low level of the bilirubin-processing enzyme that causes Gilbert's syndrome may also increase the side effects of certain medications, since this enzyme plays a role in helping clear these medications from your body.

These medications include:

• Irinotecan (Camptosar), a cancer chemotherapy drug
• Some protease inhibitors used to treat HIV

If you have Gilbert's syndrome, talk to your doctor before taking new medications. Also, having any other condition that impairs the destruction of red blood cells may increase your risk of developing gallstones.