Diseases and Conditions
Klippel-Trenaunay syndrome
Overview
Symptoms
Causes
Risk factors
Complications
Diagnosis
Treatment
Lifestyle and home remedies
Coping and support
Preparing for an appointment
Causes
Klippel-Trenaunay syndrome is a genetic condition. It involves genetic changes (mutations) most commonly in the PIK3CA gene. These genetic changes are responsible for development of tissues in the body, resulting in overgrowth.
KTS is not usually inherited. The gene mutations occur randomly during cell division in early development before birth.
