Symptoms

Signs and symptoms of primary ovarian insufficiency are similar to those of menopause or estrogen deficiency. They include:

• Irregular or skipped periods, which might be present for years or develop after a pregnancy or after stopping birth control pills
• Difficulty getting pregnant
• Hot flashes
• Night sweats
• Vaginal dryness
• Dry eyes
• Irritability or difficulty concentrating
• Decreased sexual desire

When to see a doctor

If you've missed your period for three months or more, see your doctor to determine the cause. You can miss your period for a number of reasons — including pregnancy, stress, or a change in diet or exercise habits — but it's best to get evaluated whenever your menstrual cycle changes.

Even if you don't mind not having periods, it's advisable to see your doctor to find out what's causing the change. Low estrogen levels can lead to bone loss and an increased risk of heart disease.