Diseases and Conditions
Lymphoma
Overview
Symptoms
Causes
Risk factors
Diagnosis
Treatment
Alternative medicine
Coping and support
Preparing for an appointment
Causes
Doctors aren't sure what causes lymphoma. But it begins when a disease-fighting white blood cell called a lymphocyte develops a genetic mutation. The mutation tells the cell to multiply rapidly, causing many diseased lymphocytes that continue multiplying.
The mutation also allows the cells to go on living when other normal cells would die. This causes too many diseased and ineffective lymphocytes in your lymph nodes and causes the lymph nodes, spleen and liver to swell.