Diseases and Conditions
Monoclonal gammopathy of undetermined significance (MGUS)
Coping and support
Overview
Symptoms
Causes
Risk factors
Complications
Diagnosis
Treatment
Preparing for an appointment
Treatment
MGUS doesn't require treatment. But your doctor is likely to recommend periodic checkups to monitor your health, probably starting six months after your diagnosis.
Watchful waiting
If you are at high risk of MGUS developing into a more serious condition, your doctor may recommend more frequent checkups so that any progression can be diagnosed and treatment started as soon as possible.
Your doctor is likely to watch for signs and symptoms such as:
- Bone pain
- Fatigue or weakness
- Unintentional weight loss
- Fever or night sweats
- Headache, dizziness, nerve pain, or changes in vision or hearing
- Bleeding
- Anemia or other blood abnormalities
- Swollen lymph nodes, liver or spleen
Medications
If you have osteoporosis, your doctor might recommend a medication to increase bone density. Examples include alendronate (Fosamax), risedronate (Actonel, Atelvia), ibandronate (Boniva) and zoledronic acid (Reclast, Zometa).