Diseases and Conditions

Sudden cardiac arrest

Causes

The usual cause of sudden cardiac arrest is an abnormal heart rhythm (arrhythmia), which happens when your heart's electrical system isn't working correctly.

The heart's electrical system controls the rate and rhythm of your heartbeat. If something goes wrong, your heart can beat too fast, too slowly or irregularly (arrhythmia). Often these arrhythmias are brief and harmless, but some types can lead to sudden cardiac arrest.

The most common heart rhythm at the time of cardiac arrest is an arrhythmia in a lower chamber of your heart (ventricle). Rapid, erratic electrical impulses cause your ventricles to quiver uselessly instead of pumping blood (ventricle fibrillation).

Heart conditions that can lead to sudden cardiac arrest

Sudden cardiac arrest can happen in people who have no known heart disease. However, a life-threatening arrhythmia usually develops in a person with a preexisting, possibly undiagnosed heart condition. Conditions include:

  • Coronary artery disease. Most cases of sudden cardiac arrest occur in people who have coronary artery disease, in which the arteries become clogged with cholesterol and other deposits, reducing blood flow to the heart.
  • Heart attack. If a heart attack occurs, often as a result of severe coronary artery disease, it can trigger ventricular fibrillation and sudden cardiac arrest. Also, a heart attack can leave scar tissue in your heart. Electrical short circuits around the scar tissue can lead to abnormalities in your heart rhythm.
  • Enlarged heart (cardiomyopathy). This occurs primarily when your heart's muscular walls stretch and enlarge or thicken. Then your heart's muscle is abnormal, a condition that often leads to arrhythmias.
  • Valvular heart disease. Leaking or narrowing of your heart valves can lead to stretching or thickening of your heart muscle. When the chambers become enlarged or weakened because of stress caused by a tight or leaking valve, there's an increased risk of developing arrhythmia.
  • Heart defect present at birth (congenital heart disease). When sudden cardiac arrest occurs in children or adolescents, it can be due to congenital heart disease. Adults who've had corrective surgery for a congenital heart defect still have a higher risk of sudden cardiac arrest.
  • Electrical problems in the heart. In some people, the problem is in the heart's electrical system itself instead of a problem with the heart muscle or valves. These are called primary heart rhythm abnormalities and include conditions such as Brugada syndrome and long QT syndrome.